Pub. Date : 2010 Oct 14
PMID : 20708605
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The secreted Abeta was decreased and alphaAPPs was significantly increased by non-selective nAChR agonist nicotine (10 muM) and specific alpha7 nAChR agonist GTS-21 (1 muM), and APP expression was not affected. | Nicotine | latexin | Homo sapiens |
| 2 | CTF-alpha was increased and CTF-gamma was decreased when treated with nicotine (10 muM). | Nicotine | latexin | Homo sapiens |
| 3 | In addition, the results of enymatic activity analysis showed that nicotine (1muM) and GTS-21 (0.1, 1 muM) decreased gamma-secretase activity, but has no effects on alpha-secretase activity and beta-secretase activity. | Nicotine | latexin | Homo sapiens |