Title : Iron sensitizes keratinocytes and fibroblasts to UVA-mediated matrix metalloproteinase-1 through TNF-α and ERK activation.

Pub. Date : 2011 Mar

PMID : 20701626






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Iron sensitizes keratinocytes and fibroblasts to UVA-mediated matrix metalloproteinase-1 through TNF-alpha and ERK activation. Iron tumor necrosis factor Homo sapiens
2 Our results indicate that iron and UVA increase MMP-1 activity in dermal fibroblasts not only directly through ERK activation but also by an indirect paracrine loop through TNF-alpha released by NHEK. Iron tumor necrosis factor Homo sapiens