Title : Induction of autophagy by dual mTORC1-mTORC2 inhibition in BCR-ABL-expressing leukemic cells.

Pub. Date : 2010 Oct

PMID : 20699667






1 Functional Relationships(s)
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1 We have recently shown that dual targeting of mTORC1 and mTORC2 complexes using a catalytic mTOR inhibitor, OSI-027, results in generation of potent antileukemic effects against BCR-ABL transformed cells. OSI 027 CREB regulated transcription coactivator 1 Mus musculus