Title : Characterization of 17-dihydroexemestane glucuronidation: potential role of the UGT2B17 deletion in exemestane pharmacogenetics.

Pub. Date : 2010 Oct

PMID : 20697310






2 Functional Relationships(s)
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1 Characterization of 17-dihydroexemestane glucuronidation: potential role of the UGT2B17 deletion in exemestane pharmacogenetics. 17-dihydroexemestane UDP glucuronosyltransferase family 2 member B17 Homo sapiens
2 CONCLUSION: These data suggest that 17-dihydroexemestane is an active metabolite of exemestane and that the UGT2B17 deletion polymorphism could play an important role in determining levels of excretion of 17-dihydroexemestane and overall exemestane metabolism. 17-dihydroexemestane UDP glucuronosyltransferase family 2 member B17 Homo sapiens