Title : Pharmacological characterisation of the GlyT-1 glycine transporter using two novel radioligands.

Pub. Date : 2010 Nov

PMID : 20691713






1 Functional Relationships(s)
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Protein Name
Organism
1 Glycine produced concentration-dependent decreases in binding affinity of both radioligands without major changes in B(max) values, suggesting that both [(3)H]-SB-733993 and [(3)H]-GSK931145 bind to sites on GlyT-1 that are orthosteric to the site at which glycine itself binds. Glycine solute carrier family 6 member 9 Rattus norvegicus