Pub. Date : 2010 Aug
PMID : 20689757
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We hypothesized that assessing the gene expression of the chemotherapy response modifiers multidrug resistance gene 1 (MDR1) and excision repair cross-complementing 1 (ERCC1) may help identify the group of patients benefiting from cisplatin-based adjuvant chemotherapy. | Cisplatin | ERCC excision repair 1, endonuclease non-catalytic subunit | Homo sapiens |
2 | We hypothesized that assessing the gene expression of the chemotherapy response modifiers multidrug resistance gene 1 (MDR1) and excision repair cross-complementing 1 (ERCC1) may help identify the group of patients benefiting from cisplatin-based adjuvant chemotherapy. | Cisplatin | ERCC excision repair 1, endonuclease non-catalytic subunit | Homo sapiens |
3 | CONCLUSIONS: High MDR1 and ERCC1 gene expressions are associated with inferior outcome after cisplatin-based adjuvant chemotherapy for locally advanced bladder cancer. | Cisplatin | ERCC excision repair 1, endonuclease non-catalytic subunit | Homo sapiens |