Title : Identification of the first low-molecular-weight inhibitors of matriptase-2.

Pub. Date : 2010 Aug 12

PMID : 20684597






1 Functional Relationships(s)
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1 Two N-protected dipeptide amides containing a 4-amidinobenzylamide as P1 residue (compounds 1 and 3) were identified as the first small molecule inhibitors of matriptase-2 with K(i) values of 170 and 460 nM, respectively. 4-amidinobenzylamide transmembrane serine protease 6 Homo sapiens