Title : TGF-β1 prevents up-regulation of the P2X7 receptor by IFN-γ and LPS in leukemic THP-1 monocytes.

Pub. Date : 2010 Nov

PMID : 20670615






1 Functional Relationships(s)
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1 Co-incubation of cells with TGF-beta1 plus IFN-gamma and LPS prevented the up-regulation of P2X7 expression and ATP-induced ethidium(+) uptake in a concentration-dependent fashion with a maximum effect at 5ng/ml and with an IC(50) of ~0.4ng/ml. Ethidium transforming growth factor beta 1 Homo sapiens