Title : Ganglioside DSGb5, preferred ligand for Siglec-7, inhibits NK cell cytotoxicity against renal cell carcinoma cells.

Pub. Date : 2010 Nov

PMID : 20663960






1 Functional Relationships(s)
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1 In contrast, the sialic acid-binding site of Siglec-7 on NK cells was masked by cis interactions with endogenous sialoconjugates at the cell surface, but it could be unmasked by sialidase treatment of the NK cells. N-Acetylneuraminic Acid sialic acid binding Ig like lectin 7 Homo sapiens