Title : Agents for the treatment of heparin-induced thrombocytopenia.

Pub. Date : 2010 Aug

PMID : 20659659






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1 This review proposes that alternative anticoagulants (danaparoid, fondaparinux) that share certain properties of heparin-namely its irreversible antithrombin-mediated inhibition of factor Xa-and that have relatively long half-lives, have several advantages in the therapy for HIT over short-acting agents that inhibit thrombin directly (recombinant hirudin, argatroban, and bivalirudin). Fondaparinux serpin family C member 1 Homo sapiens