Title : Relationship among superoxide-related enzyme, PPARs, and endothelium-dependent relaxation in murine aortas previously organ-cultured in high-glucose conditions.

Pub. Date : 2010 Jul

PMID : 20651824






1 Functional Relationships(s)
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1 These results suggest that in the mouse aorta, exposure to high glucose levels may lead to an excessive generation of superoxide via increased gp91phox and decreased Mn-SOD protein expression and that this may in turn trigger an impairment of endothelium-dependent relaxation. Superoxides paired Ig-like receptor B Mus musculus