Title : 64Cu-1,4,7,10-4,11-Bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane-rhenium-cyclized-[Cys3,4,10,D-Phe7,Arg11]α-MSH3-13

Pub. Date : 2004

PMID : 20641610






2 Functional Relationships(s)
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1 To improve the tumor/kidney uptake ratio and metabolic stability, a rhenium-cyclized alpha-MSH analog, Re-[Cys(3,4,10),D-Phe(7),Arg(11)]alpha-MSH3-13 (Re-CCMSH(Arg(11))), was conjugated with bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane (CBTE2A). Arginine proopiomelanocortin Homo sapiens
2 To improve the tumor/kidney uptake ratio and metabolic stability, a rhenium-cyclized alpha-MSH analog, Re-[Cys(3,4,10),D-Phe(7),Arg(11)]alpha-MSH3-13 (Re-CCMSH(Arg(11))), was conjugated with bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane (CBTE2A). Arginine proopiomelanocortin Homo sapiens