Title : (S)-N-(1-Ethyl-2-pyrrolidinyl)methyl)-5-bromo-2-[11C]methoxy-3-methoxybenzamide

Pub. Date : 2004

PMID : 20641188






2 Functional Relationships(s)
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1 In binding studies, (123)I-labeled epidepride, an analog of isoremoxipride, was found to have high potency and low nonspecific binding, and to be selective for striatal and extrastriatal D2 receptors (9). FLB 457 immunoglobulin heavy diversity 2-15 Homo sapiens
2 (S)-N-(1-Ethyl-2-pyrrolidinyl)methyl)-5-bromo-2,3-dimethoxybenzamide (FLB 457, or isoremoxipride) had very high affinity for D2 (Ki = 0.017 nM) and D3 (Ki = 0.022 nM) receptors but not other neurotransmitter receptors (14). FLB 457 immunoglobulin heavy diversity 2-15 Homo sapiens