Title : Tracking human contact allergens: from mass spectrometric identification of peptide-bound reactive small chemicals to chemical-specific naive human T-cell priming.

Pub. Date : 2010 Oct

PMID : 20631061






2 Functional Relationships(s)
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1 Here, we analyze the molecular conditions for adduct formation of the strong human contact sensitizer 2,4-dinitrochlorobenzene (DNCB) and its water-soluble form, 2,4-dinitrobenzenesulfonic acid (DNBS), with both an all amino acid-containing model peptide (+- Cys) and the protein human serum albumin (HSA). Dinitrochlorobenzene albumin Homo sapiens
2 Here, we analyze the molecular conditions for adduct formation of the strong human contact sensitizer 2,4-dinitrochlorobenzene (DNCB) and its water-soluble form, 2,4-dinitrobenzenesulfonic acid (DNBS), with both an all amino acid-containing model peptide (+- Cys) and the protein human serum albumin (HSA). Dinitrochlorobenzene albumin Homo sapiens