Title : Temperature-responsive release of cortisol from its binding globulin: a protein thermocouple.

Pub. Date : 2010 Oct

PMID : 20631013






2 Functional Relationships(s)
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1 This mechanism has been noted to be temperature responsive, and we have now investigated the effects of temperature on the binding of human CBG to both cortisol and progesterone. Progesterone serpin family A member 6 Homo sapiens
2 METHODS: Recombinant human CBG was synthesized and used for binding studies with cortisol and progesterone between 34 and 43 C. Binding was monitored by recording the change in intrinsic protein fluorescence. Progesterone serpin family A member 6 Homo sapiens