Title : Methylation of the tumor suppressor protein, BRCA1, influences its transcriptional cofactor function.

Pub. Date : 2010 Jun 29

PMID : 20614009






1 Functional Relationships(s)
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1 METHODS/PRINCIPAL FINDINGS: Here we demonstrate for the first time that BRCA1 is methylated both in breast cancer cell lines and breast cancer tumor samples at arginine and lysine residues through immunoprecipitation and western blot analysis. Arginine BRCA1 DNA repair associated Homo sapiens