Title : Enhancement of transcriptional activity of mutant p53 tumor suppressor protein through stabilization of tetramer formation by calix[6]arene derivatives.

Pub. Date : 2010 Aug 1

PMID : 20605095






1 Functional Relationships(s)
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1 In this study, we report, for the first time, the enhancement of the in vivo transcriptional activity of the most common Li-Fraumeni p53 mutant by imidazole-calix[6]arene through stabilization of the oligomer formation. imidazole-calix[6] tumor protein p53 Homo sapiens