Title : Identification of common predictive markers of in vitro response to the Mek inhibitor selumetinib (AZD6244; ARRY-142886) in human breast cancer and non-small cell lung cancer cell lines.

Pub. Date : 2010 Jul

PMID : 20587667






1 Functional Relationships(s)
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1 In total, these results suggest that clinical trials of selumetinib in breast cancer and NSCLC might select patients whose tumors harbor raf and ras mutations, respectively. AZD 6244 zinc fingers and homeoboxes 2 Homo sapiens