Title : DNA repair signature is associated with anthracycline response in triple negative breast cancer patients.

Pub. Date : 2010 Aug

PMID : 20582464






1 Functional Relationships(s)
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1 We hypothesized that a subset of sporadic triple negative (TN) breast cancer patients whose tumors have defective DNA repair similar to BRCA1-associated tumors are more likely to exhibit up-regulation of DNA repair-related genes, anthracycline-sensitivity, and taxane-resistance. Anthracyclines BRCA1 DNA repair associated Homo sapiens