Title : Risk of diarrhoea in a long-term cohort of renal transplant patients given mycophenolate mofetil: the significant role of the UGT1A8 2 variant allele.

Pub. Date : 2010 Jun

PMID : 20565459






1 Functional Relationships(s)
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1 CONCLUSION: These results suggest that a possible inhibition of biliary excretion of MPA metabolites by CsA and a decreased intestinal production of these metabolites in UGT1A8 2 carriers may be protective factors against MMF-induced diarrhoea. Mycophenolic Acid UDP glucuronosyltransferase family 1 member A8 Homo sapiens