Pub. Date : 2010 Oct
PMID : 20558222
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | [(14)C]Glycine uptake by TR-MUL5 cells was Na(+)- and Cl(-)-dependent, and a saturable process with Michaelis-Menten constants of 48.6 microM and 4.53 mM, and inhibited by glycine transporter 1 (GlyT1) and system A substrates. | Glycine | solute carrier family 6 member 9 | Rattus norvegicus |
| 2 | [(14)C]Glycine uptake by TR-MUL5 cells was Na(+)- and Cl(-)-dependent, and a saturable process with Michaelis-Menten constants of 48.6 microM and 4.53 mM, and inhibited by glycine transporter 1 (GlyT1) and system A substrates. | Glycine | solute carrier family 6 member 9 | Rattus norvegicus |
| 3 | These uptake studies suggest that GlyT1 and system A are involved in [(14)C]glycine uptake for the high- and low-affinity processes, respectively, in TR-MUL5 cells. | Glycine | solute carrier family 6 member 9 | Rattus norvegicus |
| 4 | In conclusion, GlyT1 and CAT1 most likely mediate glycine and L-arginine uptake, respectively, by Muller cells and are expected to play an important role in supplying precursors for creatine biosynthesis in Muller cells. | Glycine | solute carrier family 6 member 9 | Rattus norvegicus |