Pub. Date : 2010 Aug
PMID : 20554235
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of glycogen biosynthesis via mTORC1 suppression as an adjunct therapy for Pompe disease. | Glycogen | CREB regulated transcription coactivator 1 | Mus musculus |
| 2 | Co-administration of the mTORC1 inhibitor rapamycin with rhGAA in a GAA knockout mouse reduced muscle glycogen content more than rhGAA or rapamycin alone. | Glycogen | CREB regulated transcription coactivator 1 | Mus musculus |
| 3 | These results suggest mTORC1 inhibition may benefit GSDs that involve glycogen accumulation in muscle. | Glycogen | CREB regulated transcription coactivator 1 | Mus musculus |