Title : Icariin attenuates LPS-induced acute inflammatory responses: involvement of PI3K/Akt and NF-kappaB signaling pathway.

Pub. Date : 2010 Sep 10

PMID : 20519138






2 Functional Relationships(s)
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1 However, the protective effects of icariin were reversed by a PI3K/Akt inhibitor (wortmannin). icariin thymoma viral proto-oncogene 1 Mus musculus
2 Our in vitro and in vivo results suggested that activation of the PI3K/Akt pathway and the inhibition of NF-kappaB were involved in the protective effects of icariin on LPS-induced acute inflammatory responses. icariin thymoma viral proto-oncogene 1 Mus musculus