Title : Combined inhibitory effects of soy isoflavones and curcumin on the production of prostate-specific antigen.

Pub. Date : 2010 Jul 1

PMID : 20503397






6 Functional Relationships(s)
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1 Combined inhibitory effects of soy isoflavones and curcumin on the production of prostate-specific antigen. Isoflavones kallikrein related peptidase 3 Homo sapiens
2 RESULTS: The production of PSA were markedly decreased by the combined treatment of isoflavones and curcumin in prostate cancer cell line, LNCaP. Isoflavones kallikrein related peptidase 3 Homo sapiens
3 In clinical trials, PSA levels decreased in the patients group with PSA >or= 10 treated with supplement containing isoflavones and curcumin (P = 0.01). Isoflavones kallikrein related peptidase 3 Homo sapiens
4 In clinical trials, PSA levels decreased in the patients group with PSA >or= 10 treated with supplement containing isoflavones and curcumin (P = 0.01). Isoflavones kallikrein related peptidase 3 Homo sapiens
5 CONCLUSIONS: Our results indicated that isoflavones and curcumin could modulate serum PSA levels. Isoflavones kallikrein related peptidase 3 Homo sapiens
6 Curcumin presumably synergizes with isoflavones to suppress PSA production in prostate cells through the anti-androgen effects. Isoflavones kallikrein related peptidase 3 Homo sapiens