Pub. Date : 2010 Jul
PMID : 20484465
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Pharmacological or molecular intervention of protein kinase A (PKA) or ERK1/2 completely abolished genistein-stimulated beta-cell proliferation, suggesting that both molecules are essential for genistein action. | Genistein | mitogen-activated protein kinase 3 | Mus musculus |
2 | These results demonstrate that genistein may be a natural antidiabetic agent by directly modulating pancreatic beta-cell function via activation of the cAMP/PKA-dependent ERK1/2 signaling pathway. | Genistein | mitogen-activated protein kinase 3 | Mus musculus |