Title : Vitamin A deficiency results in dysregulation of lipid efflux pathway in rat kidney.

Pub. Date : 2010 Aug

PMID : 20480185






3 Functional Relationships(s)
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1 Lipid metabolism involved in renal reverse cholesterol transport may be mediated by decreasing the signaling through the ABCA1 cholesterol efflux pathway, which is significantly modified in kidneys of vitamin A-deficient rats. Cholesterol ATP binding cassette subfamily A member 1 Rattus norvegicus
2 Compared with the control, VAD rats had significantly higher levels of transforming growth factor-beta 1 and lower levels of ABCA1, a key gene involved in cholesterol efflux and tissue lipid homeostasis. Cholesterol ATP binding cassette subfamily A member 1 Rattus norvegicus
3 Lipid metabolism involved in renal reverse cholesterol transport may be mediated by decreasing the signaling through the ABCA1 cholesterol efflux pathway, which is significantly modified in kidneys of vitamin A-deficient rats. Cholesterol ATP binding cassette subfamily A member 1 Rattus norvegicus