Pub. Date : 2010 Jun
PMID : 20451353
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: In A375 cells, CD147 silencing increased the H(2)O(2)-induced inhibition of cell viability, H(2)O(2)-induced apoptosis, H(2)O(2)-mediated ROS- and MDA generation, and the H(2)O(2)-triggered decrease in SOD activity. | Reactive Oxygen Species | basigin (Ok blood group) | Homo sapiens |
| 2 | CONCLUSIONS: Our results demonstrated that CD147 silencing increased cellular ROS and destroyed the intrinsic antioxidant defenses in A375, indicating that CD147 exerts a cytoprotective effect against H(2)O(2)-induced oxidative damage. | Reactive Oxygen Species | basigin (Ok blood group) | Homo sapiens |
| 3 | CONCLUSIONS: Our results demonstrated that CD147 silencing increased cellular ROS and destroyed the intrinsic antioxidant defenses in A375, indicating that CD147 exerts a cytoprotective effect against H(2)O(2)-induced oxidative damage. | Reactive Oxygen Species | basigin (Ok blood group) | Homo sapiens |