Pub. Date : 2010 Jun 15
PMID : 20444629
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the present study we report that salinomycin acts as a potent inhibitor of multidrug resistance gp170, as evidenced through drug efflux assays in MDR cancer cell lines overexpressing P-gp (CEM-VBL 10 and CEM-VBL 100; A2780/ADR). | salinomycin | phosphoglycolate phosphatase | Homo sapiens |
| 2 | Conformational P-gp assay provided evidence that the inhibitory effect of salinomycin on P-gp function could be mediated by the induction of a conformational change of the ATP transporter. | salinomycin | phosphoglycolate phosphatase | Homo sapiens |
| 3 | Conformational P-gp assay provided evidence that the inhibitory effect of salinomycin on P-gp function could be mediated by the induction of a conformational change of the ATP transporter. | salinomycin | phosphoglycolate phosphatase | Homo sapiens |