CPRiL

4 Functional Relationships(s) Download
	Sentence	Compound Name	Protein Name	Organism
1	PP2, a specific inhibitor of Src family protein tyrosine kinases (SrcPTKs), not only attenuated the Abeta25-35-induced increases in the tyrosine phosphorylation of NR2A and in the associations among Src, NR2A, and PSD-95, but also protected against neuronal loss in the CA1 region.	Tyrosine	SRC proto-oncogene, non-receptor tyrosine kinase	Rattus norvegicus
2	PP2, a specific inhibitor of Src family protein tyrosine kinases (SrcPTKs), not only attenuated the Abeta25-35-induced increases in the tyrosine phosphorylation of NR2A and in the associations among Src, NR2A, and PSD-95, but also protected against neuronal loss in the CA1 region.	Tyrosine	SRC proto-oncogene, non-receptor tyrosine kinase	Rattus norvegicus
3	These results suggest that the activation of NMDA receptors after Abeta treatment promotes the formation of NR2A-PSD-95-Src complex and thus increases the tyrosine phosphorylation of NR2A by Src kinases, which up-regulates the function of NMDA receptors.	Tyrosine	SRC proto-oncogene, non-receptor tyrosine kinase	Rattus norvegicus
4	These results suggest that the activation of NMDA receptors after Abeta treatment promotes the formation of NR2A-PSD-95-Src complex and thus increases the tyrosine phosphorylation of NR2A by Src kinases, which up-regulates the function of NMDA receptors.	Tyrosine	SRC proto-oncogene, non-receptor tyrosine kinase	Rattus norvegicus