Pub. Date : 2010 Oct
PMID : 20435347
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | FLT3 and KIT mutated pediatric acute myeloid leukemia (AML) samples are sensitive in vitro to the tyrosine kinase inhibitor SU11657. | SU 11657 | KIT proto-oncogene, receptor tyrosine kinase | Homo sapiens |
| 2 | FLT3 and KIT mutated samples were significantly more sensitive to SU11657 than WT KIT and FLT3 samples. | SU 11657 | KIT proto-oncogene, receptor tyrosine kinase | Homo sapiens |
| 3 | Samples without KIT or FLT3 mutations, but with a high wild-type (WT) KIT expression were significantly more sensitive to SU11657 than samples with low KIT expression. | SU 11657 | KIT proto-oncogene, receptor tyrosine kinase | Homo sapiens |
| 4 | Samples without KIT or FLT3 mutations, but with a high wild-type (WT) KIT expression were significantly more sensitive to SU11657 than samples with low KIT expression. | SU 11657 | KIT proto-oncogene, receptor tyrosine kinase | Homo sapiens |