Title : Changes in the QTc interval after administration of flecainide acetate, with and without coadministered paroxetine, in relation to cytochrome P450 2D6 genotype: data from an open-label, two-period, single-sequence crossover study in healthy Korean male subjects.

Pub. Date : 2010 Apr

PMID : 20435235






1 Functional Relationships(s)
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1 OBJECTIVE: This study evaluated QTc-interval changes after administration of a single oral dose of flecainide, with and without paroxetine, in relation to CYP2D6 genetic polymorphism. qtc cytochrome P450 family 2 subfamily D member 6 Homo sapiens