Title : 1alpha,25-Dihydroxyvitamin D3 affects hormone production and expression of steroidogenic enzymes in human adrenocortical NCI-H295R cells.

Pub. Date : 2010 Sep

PMID : 20420936






1 Functional Relationships(s)
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1 The current data indicate that the 1alpha,25-dihydroxyvitamin D(3)-mediated decrease in corticosterone and androgen production is due to suppression of the 21-hydroxylase activity by CYP21A2 and the 17,20-lyase activity by CYP17A1, respectively. Calcitriol cytochrome P450 family 21 subfamily A member 2 Homo sapiens