Title : [Influence of celecoxib combined with IFN-alpha on proliferation, apoptosis, cell cycle and CD117 expression of K562 cells].

Pub. Date : 2010 Apr

PMID : 20416162






3 Functional Relationships(s)
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1 [Influence of celecoxib combined with IFN-alpha on proliferation, apoptosis, cell cycle and CD117 expression of K562 cells]. Celecoxib KIT proto-oncogene, receptor tyrosine kinase Homo sapiens
2 The aim of this study was to investigate the effects of Celecoxib on the proliferation, apoptosis, cell cycle and CD117 expression of K562 cells, and to explore its synergistic effect with IFN-alpha. Celecoxib KIT proto-oncogene, receptor tyrosine kinase Homo sapiens
3 In conclusion, Celecoxib and IFN-alpha both may inhibit K562 cell proliferation, induce apoptosis, reduce CD117 expression and produce G0/G1 phase block to various degree and the two drugs have a synergistic effect. Celecoxib KIT proto-oncogene, receptor tyrosine kinase Homo sapiens