Title : Oleanolic acid and ursolic acid induce apoptosis in HuH7 human hepatocellular carcinoma cells through a mitochondrial-dependent pathway and downregulation of XIAP.

Pub. Date : 2010 May 26

PMID : 20415421






1 Functional Relationships(s)
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1 OA and UA-induced apoptosis involving the release of mitochondria cytochrome c into the cytosol and subsequently induced the activation of caspase-9 and caspase-3, followed by cleavage of poly (ADP-ribose) polymerase (PARP). ursolic acid cytochrome c, somatic Homo sapiens