Title : The histone deacetylase inhibitor MGCD0103 induces apoptosis in B-cell chronic lymphocytic leukemia cells through a mitochondria-mediated caspase activation cascade.

Pub. Date : 2010 May

PMID : 20406947






1 Functional Relationships(s)
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1 MGCD0103 decreased the expression of Mcl-1 and induced translocation of Bax to the mitochondria, mitochondrial depolarization, and release of cytochrome c in the cytosol. mocetinostat cytochrome c, somatic Homo sapiens