Title : Synthetic triterpenoids inhibit growth, induce apoptosis and suppress pro-survival Akt, mTOR and NF-{kappa}B signaling proteins in colorectal cancer cells.

Pub. Date : 2010 Mar

PMID : 20392997






1 Functional Relationships(s)
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1 Induction of apoptosis by CDDO-Me was associated with the inhibition of pro-survival Akt, NF-kappaB and mTOR signaling proteins and NF-kappaB-regulated anti-apoptotic Bcl-2, Bcl-xL, Bad and survivin. bardoxolone methyl AKT serine/threonine kinase 1 Homo sapiens