Title : Lipotoxicity, fatty acid uncoupling and mitochondrial carrier function.

Pub. Date : 2010 Jun-Jul

PMID : 20388489






1 Functional Relationships(s)
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1 Unlike the other members of the mitochondrial carrier superfamily, the eutherian uncoupling protein UCP1 has evolved to achieve its heat-generating capacity in the physiological context provided by the brown adipocyte and therefore it is activated by the low fatty acid concentrations generated by the noradrenaline-stimulated lipolysis. Fatty Acids uncoupling protein 1 Homo sapiens