Title : Selective cytotoxicity to HER2-positive tumor cells by a recombinant e23sFv-TD-tBID protein containing a furin cleavage sequence.

Pub. Date : 2010 Apr 15

PMID : 20371697






1 Functional Relationships(s)
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1 EXPERIMENTAL DESIGN: Recombinant e23sFv-TD-tBID, consisting of a single-chain anti-HER2 antibody fragment linked to a human active truncated Bid by a 10-amino acid residue furin cleavage sequence, was bacterially expressed. tBID furin, paired basic amino acid cleaving enzyme Homo sapiens