Title : Deoxynivalenol affects in vitro intestinal epithelial cell barrier integrity through inhibition of protein synthesis.

Pub. Date : 2010 Jun 15

PMID : 20362602






1 Functional Relationships(s)
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1 These results demonstrate a dual toxicological effect of DON on differentiated Caco-2 cells consisting in an inhibition of protein synthesis as well as an increase in monolayer permeability, and moreover suggest a possible link between them through diminished synthesis of the tight junction constituent claudin-4. deoxynivalenol claudin 4 Homo sapiens