Title : Coordination of Cu(2+)and Ni(2+) with the histone model peptide of H2B N-terminal tail (1-31 residues): A spectroscopic study.

Pub. Date : 2010 May 14

PMID : 20358093






1 Functional Relationships(s)
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1 Cu(2+) and Ni(2+) binding to the N-terminal tail of H2B causes a severe conformational change that might interfere with histone post-translational modifications, possibly leading to epigenetic changes. Nickel(2+) H2B clustered histone 21 Homo sapiens