Title : Acquired resistance to temozolomide in glioma cell lines: molecular mechanisms and potential translational applications.

Pub. Date : 2010

PMID : 20357518






2 Functional Relationships(s)
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Protein Name
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1 In clonogenic and MTT assays, methylguanine methyltransferase (MGMT) depletion using O6-benzylguanine sensitized U373VR cells to temozolomide, indicating the resistance mechanism involves MGMT re-expression. monooxyethylene trimethylolpropane tristearate O-6-methylguanine-DNA methyltransferase Homo sapiens
2 In clonogenic and MTT assays, methylguanine methyltransferase (MGMT) depletion using O6-benzylguanine sensitized U373VR cells to temozolomide, indicating the resistance mechanism involves MGMT re-expression. monooxyethylene trimethylolpropane tristearate O-6-methylguanine-DNA methyltransferase Homo sapiens