Title : The Rab11 pathway is required for influenza A virus budding and filament formation.

Pub. Date : 2010 Jun

PMID : 20357086






2 Functional Relationships(s)
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1 We find that cellular Rab11 (a small GTP-binding protein involved in endocytic recycling) and Rab11-family interacting protein 3 ([FIP3] which plays a role in membrane trafficking and regulation of actin dynamics) are both required to support the formation of filamentous virions, while Rab11 is additionally involved in the final budding step of spherical particles. Guanosine Triphosphate RAB11A, member RAS oncogene family Homo sapiens
2 We find that cellular Rab11 (a small GTP-binding protein involved in endocytic recycling) and Rab11-family interacting protein 3 ([FIP3] which plays a role in membrane trafficking and regulation of actin dynamics) are both required to support the formation of filamentous virions, while Rab11 is additionally involved in the final budding step of spherical particles. Guanosine Triphosphate RAB11A, member RAS oncogene family Homo sapiens