Title : Alkylation of acetylcholinesterase anionic centre with aziridinium ion accelerates the enzyme acylation step.

Pub. Date : 1991 Apr 29

PMID : 2029540






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Affinity labelling of acetylcholinesterase (EC 3.1.1.7, acetylcholine acetylhydrolase) anionic centre with N,N-dimethyl-2-phenylaziridinium ion accelerates the hydrolysis of non-ionic acetic esters by increasing the rate of the enzyme acylation step at least 500-times while the rate of the deacylation step remains unchanged. ethyl acetate acetylcholinesterase (Cartwright blood group) Homo sapiens