Title : A new class of potent thrombin inhibitors that incorporates a scissile pseudopeptide bond.

Pub. Date : 1991 Apr 22

PMID : 2026264






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The P1" subsite of P79 is isosteric with the glycine residue of the natural thrombin substrate fibrinogen, but is proteolytically stable due to the incorporation of a ketomethylene pseudopeptide bond. Glycine coagulation factor II, thrombin Bos taurus