Title : Direct and indirect effects of cannabinoids on in vitro GABA release in the rat arcuate nucleus.

Pub. Date : 2010 Jun

PMID : 20236227






1 Functional Relationships(s)
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1 The inhibitory effect of rimonabant was also prevented by naloxone and a kappa-opioid receptor selective antagonist, suggesting that GABA release from arcuate NPY/AgRP/GABA neurones can be inhibited by endogenous opioid peptides, and that the release of opioid peptides is sensitive to cannabinoids. Rimonabant neuropeptide Y Rattus norvegicus