Title : Pertussis toxin up-regulates angiotensin type 1 receptors through Toll-like receptor 4-mediated Rac activation.

Pub. Date : 2010 May 14

PMID : 20231290






1 Functional Relationships(s)
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1 PTX increased the expression of IL-1beta and AT1R through NF-kappaB, and a small GTP-binding protein, Rac, mediated PTX-induced NF-kappaB activation through NADPH oxidase-dependent production of reactive oxygen species. Guanosine Triphosphate AKT serine/threonine kinase 1 Homo sapiens