Title : Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase.

Pub. Date : 2010 Jun

PMID : 20228137






1 Functional Relationships(s)
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1 We observed that metformin blocked the effect of the high-energy diet on tumor growth, reduced insulin levels, and attenuated the effect of diet on phosphorylation of AKT and expression of FASN. Metformin thymoma viral proto-oncogene 1 Mus musculus