Title : CYP4F2 gene V433M polymorphism is associated with ischemic stroke in the male Northern Chinese Han population.

Pub. Date : 2010 May 30

PMID : 20227456






1 Functional Relationships(s)
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1 BACKGROUND: CYP4F2 is a member of the cytochrome P450 enzymes and is responsible for metabolizing arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE); 20-HETE plays a role in the regulation of vascular tone in the cerebral, coronary, and renal circulation. Arachidonic Acid cytochrome P450 family 4 subfamily F member 2 Homo sapiens