Title : Co-evolution-driven switch of J-protein specificity towards an Hsp70 partner.

Pub. Date : 2010 May

PMID : 20224575






1 Functional Relationships(s)
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1 Here, we report that existence of the Hsp70 Ssq1, which arose by duplication of the gene encoding multifunction mtHsp70 and specializes in iron-sulphur cluster biogenesis, correlates with functional and structural changes in the J domain of its J-protein partner Jac1. Iron Hsp70 family ATPase SSQ1 Saccharomyces cerevisiae S288C