Pub. Date : 2010 Jun
PMID : 20211938
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TCDD exposure decreased the frequency and number of splenic CD11c(high) DCs on day 7 when compared with vehicle-treated controls. | Polychlorinated Dibenzodioxins | integrin alpha X | Mus musculus |
| 2 | TCDD increased the expression of CD86 and CD54, while decreasing the frequency of splenic CD11c(high) DCs expressing CD11a and major histocompatibility complex (MHC) class II. | Polychlorinated Dibenzodioxins | integrin alpha X | Mus musculus |
| 3 | Moreover, TCDD selectively decreased the CD11c(high)CD8alpha(-)33D1(+) splenic DCs specialized at activating CD4(+) T cells but did not affect the regulatory CD11c(high)CD8alpha(+)DEC205(+) splenic DCs. | Polychlorinated Dibenzodioxins | integrin alpha X | Mus musculus |